SCHEMBL28292019

SCHEMBL28292019

Oc1ccc(-c2ccccc2O)cc1.[KH]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 2/20 0.68
ALDH1A1 P00352 2/20 0.68
HPGD P15428 2/20 0.68
HSD17B10 Q99714 2/20 0.68
ESR2 Q92731 4/20 0.61
ABL1 P00519 2/20 0.58
ABCB1 P08183 2/20 0.58
BCR P11274 2/20 0.58
ALOX5 P09917 1/20 0.54
MMP3 P08254 1/20 0.52
KDM1A O60341 1/20 0.50
ESR1 P03372 4/20 0.48
PIM1 P11309 1/20 0.45
APP P05067 1/20 0.44
BACE1 P56817 2/20 0.44
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31166650 0.97 BCL2L1 (0.71) BCL2L1ALDH1A1HPGDHSD17B10ESR2
SCHEMBL250077 0.97 BCL2L1 (0.71) BCL2L1ALDH1A1HPGDHSD17B10ESR2
SCHEMBL21154637 0.95 BCL2L1 (0.68) BCL2L1ALDH1A1HPGDHSD17B10ESR2
Methane SCHEMBL28136772 0.95 BCL2L1 (0.68) BCL2L1ALDH1A1HPGDHSD17B10ESR2
Ethane SCHEMBL23013714 0.93 BCL2L1 (0.65) BCL2L1ALDH1A1HPGDHSD17B10ESR2
Formaldehyde SCHEMBL11761962 0.91 BCL2L1 (0.62) BCL2L1ALDH1A1HPGDHSD17B10ESR2
Formaldehyde SCHEMBL28907168 0.91 BCL2L1 (0.62) BCL2L1ALDH1A1HPGDHSD17B10ESR2
2-Phenylphenol SCHEMBL7592426 0.91 BCL2L1 (0.77) BCL2L1ALDH1A1HPGDHSD17B10ESR2
SCHEMBL714236 0.89 ALDH1A1 (0.83) BCL2L1ALDH1A1HPGDHSD17B10ESR2
SCHEMBL29443997 0.89 ALDH1A1 (0.83) BCL2L1ALDH1A1HPGDHSD17B10ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721548-A A kind of preparation method of Fluoxastrobin 南通泰禾化工股份有限公司 2019-05-07 CN disclosed