Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65199 | 0.91 | TDP1 (0.61) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL28096691 | 0.83 | ERN1 (0.65) | TDP1GPR35ERN1ALDH1A1TSHR | |
| SCHEMBL4278339 | 0.81 | TDP1 (0.50) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29448254 | 0.80 | TDP1 (0.60) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8519148 | 0.80 | S100A4 (0.55) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL24548 | 0.80 | TDP1 (0.60) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| Formamide SCHEMBL10940610 | 0.78 | HSD17B10 (0.48) | TDP1GPR35ERN1ALDH1A1TSHR | |
| Formamide SCHEMBL10940601 | 0.78 | HSD17B10 (0.48) | TDP1GPR35ERN1ALDH1A1TSHR | |
| SCHEMBL29273179 | 0.78 | ERN1 (0.49) | TDP1GPR35ERN1ALDH1A1TSHR | |
| SCHEMBL27861738 | 0.78 | TDP1 (0.50) | TDP1GPR35ERN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761944-A | A kind of chrysin amide derivatives and preparation method thereof and medical usage | 武汉翼博济生生物科技有限公司 | 2019-05-17 | — | — | CN | claimed |