SCHEMBL28292065

SCHEMBL28292065

CCN(C)C=Nc1cc(C)c(Cc2c(Cl)cccc2Cl)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
KMT2A Q03164 1/20 0.35
HTT P42858 2/20 0.34
POLB P06746 1/20 0.34
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28872668 0.87 PNMT (0.33) KMT2ATAAR1
SCHEMBL28292049 0.87 SMN1; SMN2 (0.35) LMNAKMT2AHTTSMN1; SMN2KDM4E
SCHEMBL28292068 0.84 TAAR1 (0.39) LMNAKMT2ASMN1; SMN2KDM4ETAAR1
SCHEMBL28292035 0.82 KMT2A (0.42) LMNAKMT2ASMN1; SMN2
SCHEMBL28293773 0.81 ENPP1 (0.33) KMT2A
SCHEMBL28292045 0.81 KMT2A (0.30) KMT2A
SCHEMBL28292062 0.81 CHRM4 (0.37) HTTPOLBKDM4E
SCHEMBL28293888 0.81 KMT2A (0.35) KMT2AHTTSMN1; SMN2
SCHEMBL28292143 0.81 SMN1; SMN2 (0.42) LMNAKMT2AHTTPOLBNPC1
SCHEMBL28293778 0.80 ESR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN claimed
CN-109843056-A 4-substituted phenylamine derivatives and their use for protecting crops against undesired phytopathogenic microorganisms 印度商皮埃企业有限公司 2019-06-04 CN disclosed