Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IAPP | P10997 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BID | P55957 | 4/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625189 | 0.86 | AKR1B1 (0.68) | AKR1B1L3MBTL1MAPTLMNAPOLB | |
| SCHEMBL28226376 | 0.83 | HDAC4 (0.47) | L3MBTL1IAPPMAPTLMNAHDAC4 | |
| SCHEMBL980893 | 0.82 | GABRA1 (0.50) | AKR1B1HDAC4HDAC2HDAC8BACE1 | |
| SCHEMBL28227328 | 0.81 | HDAC4 (0.52) | MAPTLMNATHRBHDAC4HDAC2 | |
| Ammonia Solution, Strong SCHEMBL324962 | 0.80 | GABRA1 (0.48) | AKR1B1HDAC4HDAC2HDAC8BACE1 | |
| Potassium SCHEMBL324000 | 0.80 | GABRA1 (0.48) | AKR1B1HDAC4HDAC2HDAC8BACE1 | |
| SCHEMBL266802 | 0.79 | AKR1B1 (0.68) | AKR1B1L3MBTL1IAPPMAPTLMNA | |
| SCHEMBL30176200 | 0.79 | AKR1B1 (0.68) | AKR1B1L3MBTL1IAPPMAPTLMNA | |
| SCHEMBL27485769 | 0.78 | KMT2A (0.45) | AKR1B1L3MBTL1POLBHDAC4HDAC2 | |
| SCHEMBL5022807 | 0.77 | HSPA5 (0.56) | AKR1B1L3MBTL1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734686-A | A kind of 2- replaces the process for catalytic synthesis of benzofuran compounds | 浙江万里学院 | 2019-05-10 | — | — | CN | disclosed |