Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015631 | 0.83 | AR (0.43) | KIF11KARS1RXRACCNE1CDK2 | |
| SCHEMBL22262525 | 0.78 | AR (0.38) | KIF11KARS1RXRACCNE1CDK2 | |
| SCHEMBL27844283 | 0.78 | NOX1 (0.35) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL28114067 | 0.77 | ESR1 (0.36) | KMT2AMAPTESR1ESR2CYP2C19 | |
| SCHEMBL27791463 | 0.77 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL27480490 | 0.77 | CA9 (0.36) | HSD17B10LMNAMEN1KMT2AMAPT | |
| SCHEMBL27760050 | 0.77 | BRD4 (0.36) | CYP3A4LMNAMAPTESR1ESR2 | |
| SCHEMBL12012738 | 0.77 | KIF11 (0.35) | KIF11LMNAESR1ESR2 | |
| SCHEMBL27335558 | 0.76 | KDM4E (0.46) | MAPTARESR1ESR2KDM4E | |
| SCHEMBL22298077 | 0.75 | AR (0.41) | KIF11KARS1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843291-A | synthetic retinoids (cell modulation) | 杜伦大学 | 2019-06-04 | — | — | CN | disclosed |