SCHEMBL28292252

SCHEMBL28292252

[CH2]CC(N)c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
HPGD P15428 5/20 0.41
HSD17B10 Q99714 4/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 4/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
THRB P10828 1/20 0.38
KDM4E B2RXH2 5/20 0.35
KMT2A Q03164 3/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1804899 0.82 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10CYP3A4TSHR
Hydrochloric Acid SCHEMBL28705372 0.82 ALDH1A1 (0.41) ALDH1A1HPGDHSD17B10CYP3A4TSHR
Hydrochloric Acid SCHEMBL1714903 0.81 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10CYP3A4TSHR
Water SCHEMBL28464913 0.81 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL1800225 0.79 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL12722762 0.79 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL28101433 0.79 ALDH1A1 (0.41) ALDH1A1HPGDHSD17B10CYP3A4TSHR
Hydrochloric Acid SCHEMBL2671921 0.78 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10CYP3A4TSHR
Hydrochloric Acid SCHEMBL30098278 0.77 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL9132356 0.76 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109679104-A A kind of eight amino pyrene propyl cage-type silsesquioxane silicon rubber heat-resisting auxiliary agents 沈阳化工大学 2019-04-26 CN claimed
CN-109679104-A A kind of eight amino pyrene propyl cage-type silsesquioxane silicon rubber heat-resisting auxiliary agents 沈阳化工大学 2019-04-26 CN disclosed
CN-109679104-A A kind of eight amino pyrene propyl cage-type silsesquioxane silicon rubber heat-resisting auxiliary agents 沈阳化工大学 2019-04-26 CN disclosed
CN-109679104-A A kind of eight amino pyrene propyl cage-type silsesquioxane silicon rubber heat-resisting auxiliary agents 沈阳化工大学 2019-04-26 CN disclosed