Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706561 | 0.93 | ALDH1A1 (0.65) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL7889086 | 0.90 | ESR1 (0.59) | LMNAALDH1A1TSHRESR1STS | |
| SCHEMBL28234326 | 0.90 | KDM4E (0.55) | ALDH1A1ESR1TDP1KDM4EMAPT | |
| SCHEMBL28091603 | 0.89 | NPC1 (0.61) | ALDH1A1TSHRESR1STSMAPT | |
| SCHEMBL29758278 | 0.88 | TDP1 (0.58) | LMNAALDH1A1TSHRESR1TDP1 | |
| SCHEMBL8755763 | 0.88 | TDP1 (0.58) | LMNAALDH1A1TSHRESR1TDP1 | |
| Hydrochloric Acid SCHEMBL9703682 | 0.88 | NPC1 (0.60) | ALDH1A1TSHRESR1STSMAPT | |
| Hydrochloric Acid SCHEMBL9222504 | 0.88 | NPC1 (0.60) | ALDH1A1TSHRESR1STSMAPT | |
| SCHEMBL20224700 | 0.87 | ALDH1A1 (0.57) | LMNAALDH1A1TSHRESR1CHRM1 | |
| SCHEMBL15315290 | 0.87 | KDM4E (0.59) | LMNAALDH1A1TSHRESR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721490-A | The preparation method of 2,6- naphthalenedicarboxylic acid | 上野制药株式会社 | 2019-05-07 | — | — | CN | disclosed |