SCHEMBL28292315

SCHEMBL28292315

C=CCOC(=O)C(F)(F)F.CCOC(=O)C(F)(F)F.COC(=O)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.38
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.35
PKM P14618 3/20 0.35
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MAPT P10636 4/20 0.33
THRB P10828 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
HIF1A Q16665 1/20 0.33
HTT P42858 2/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1082749 0.84 CYP3A4 (0.41) MAPK1TSHRSMN1; SMN2PKMALDH1A1
SCHEMBL11444238 0.82 CYP3A4 (0.39) MAPK1TSHRSMN1; SMN2PKMALDH1A1
Ammonia Solution, Strong SCHEMBL11233126 0.82 CYP3A4 (0.39) MAPK1TSHRSMN1; SMN2PKMALDH1A1
SCHEMBL28427366 0.82 CYP3A4 (0.39) MAPK1TSHRSMN1; SMN2PKMALDH1A1
SCHEMBL29506833 0.82 CYP3A4 (0.39) MAPK1TSHRSMN1; SMN2PKMALDH1A1
SCHEMBL28761387 0.82 CYP3A4 (0.39) MAPK1TSHRSMN1; SMN2PKMALDH1A1
Trifluoroacetic Acid SCHEMBL28119416 0.78 CYP3A4 (0.37) MAPK1TSHRSMN1; SMN2PKMALDH1A1
SCHEMBL27889607 0.78 ALDH1A1 (0.48) PKMALDH1A1NPSR1KDM4EMAPT
SCHEMBL60813 0.78
Bicarbonate SCHEMBL29063618 0.77 MAPK1 (0.39) MAPK1SMN1; SMN2PKMALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106796986-B The application of organic electronic assembly, zinc complex as the p dopant for organic electronic basis material 欧司朗OLED股份有限公司 2019-04-05 CN disclosed