Hydrazine

Hydrazine

SCHEMBL28292401

NN.Nc1ccc(N)cc1.Nc1cccc(N)c1.Nc1ccccc1N

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.63
CASP1 P29466 3/20 0.63
RECQL P46063 1/20 0.63
ALOX15 P16050 3/20 0.53
CASP7 P55210 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
TSHR P16473 1/20 0.50
MAOA P21397 4/20 0.48
CYP19A1 P11511 3/20 0.46
ALDH1A1 P00352 5/20 0.44
TDP1 Q9NUW8 4/20 0.44
HSD17B10 Q99714 4/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
MAOB P27338 4/20 0.43
MAPT P10636 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37040 0.97 CYP3A4 (0.67) CYP3A4CASP1RECQLALOX15CASP7
Ammonia Solution, Strong SCHEMBL28274246 0.95 CYP3A4 (0.63) CYP3A4CASP1RECQLALOX15CASP7
Arsenic SCHEMBL28093858 0.95 CYP3A4 (0.63) CYP3A4CASP1RECQLALOX15CASP7
Hydrochloric Acid SCHEMBL28200602 0.95 CYP3A4 (0.63) CYP3A4CASP1RECQLALOX15CASP7
Benzene SCHEMBL28235529 0.95 CYP3A4 (0.63) CYP3A4CASP1RECQLALOX15CASP7
SCHEMBL21462842 0.92 CYP3A4 (0.75) CYP3A4CASP1RECQLALOX15CASP7
Propane SCHEMBL28203858 0.88 CYP3A4 (0.55) CYP3A4CASP1RECQLALOX15CASP7
SCHEMBL28179370 0.86 ALDH1A1 (0.56) CYP3A4CASP1RECQLALOX15CASP7
SCHEMBL5472428 0.86 CYP3A4 (0.86) CYP3A4CASP1RECQLSMN1; SMN2TSHR
Phenol SCHEMBL28832302 0.84 ALDH1A1 (0.58) CYP3A4CASP1RECQLALOX15CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715728-A Adduct and application thereof 亨斯迈先进材料美国有限责任公司 2019-05-03 CN disclosed