Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455206 | 0.96 | SLC1A3 (0.41) | SLC1A3SLC1A2CPA1SLC1A1RNPEP | |
| SCHEMBL1746342 | 0.85 | SLC1A3 (0.45) | SLC1A3SLC1A2CPA1RNPEPSLC7A5 | |
| SCHEMBL1499647 | 0.80 | CA2 (0.41) | SLC1A3SLC1A2SLC1A1CA2CA1 | |
| SCHEMBL10582349 | 0.79 | SLC1A1 (0.40) | SLC1A3SLC1A2SLC1A1CA2CA1 | |
| SCHEMBL23175106 | 0.78 | SLC1A3 (0.39) | SLC1A3SLC1A2CPA1RNPEPSLC7A5 | |
| SCHEMBL11151367 | 0.77 | CA2 (0.47) | SLC1A3SLC1A2SLC1A1KISS1RCA2 | |
| SCHEMBL5527277 | 0.77 | SLC1A3 (0.33) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL18255608 | 0.76 | GRIK1 (0.46) | SLC1A3SLC1A2SLC1A1CA2CA1 | |
| SCHEMBL4650534 | 0.74 | GRIK1 (0.47) | SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL1262696 | 0.74 | CA2 (0.37) | SLC1A3SLC1A2SLC1A1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810589-A | Light converts resin combination, light conversion layer folds substrate and image display device | 东友精细化工有限公司 | 2019-05-28 | — | — | CN | disclosed |