Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599023 | 0.89 | KCNH2 (0.44) | KCNH2KDM4EMMP8CA12CA1 | |
| SCHEMBL27354703 | 0.84 | MMP8 (0.49) | LOXL2F2F10PSIP1TPSAB1 | |
| SCHEMBL4035085 | 0.84 | MEN1 (0.46) | KCNH2KDM4ESMN1; SMN2MMP8PIN1 | |
| SCHEMBL3314146 | 0.83 | ESR1 (0.40) | KCNH2F2F10MMP8CA12 | |
| SCHEMBL13884372 | 0.83 | EPHX1 (0.45) | LOXL2TPSAB1PRSS1PLG | |
| SCHEMBL29503075 | 0.82 | ESR1 (0.52) | KCNH2KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL29401252 | 0.82 | ESR1 (0.52) | KCNH2KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL10144789 | 0.82 | ESR1 (0.52) | KCNH2KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL9723093 | 0.81 | CA12 (0.50) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL512726 | 0.81 | MAPT (0.46) | KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574906-A | A kind of preparation method of 3,3 '-two Indoleacetic esters | 兰州大学 | 2019-04-05 | — | — | CN | disclosed |