Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 12/20 | 0.68 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292696 | 0.95 | TLR2 (0.67) | TLR2SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL28291242 | 0.95 | TLR2 (0.67) | TLR2SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL19851861 | 0.86 | TLR2 (0.69) | TLR2SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL19839674 | 0.86 | TLR2 (0.76) | TLR2SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL19839671 | 0.86 | TLR2 (0.76) | TLR2SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL28292695 | 0.85 | TLR2 (0.51) | TLR2SIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL19839897 | 0.85 | TLR2 (0.92) | TLR2SIRT2SIRT1SIRT3 | |
| SCHEMBL19839899 | 0.85 | TLR2 (0.92) | TLR2SIRT2SIRT1SIRT3 | |
| Hydrochloric Acid SCHEMBL19839828 | 0.84 | TLR2 (0.90) | TLR2SIRT2SIRT1SIRT3 | |
| Hydrochloric Acid SCHEMBL19839829 | 0.84 | TLR2 (0.90) | TLR2SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715167-A | Lipid-substituted amino 1, 2-and 1, 3-diol compounds as modulators of TLR2 dimerization | 神经孔疗法股份有限公司 | 2019-05-03 | — | — | CN | claimed |