Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 10/20 | 0.69 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851747 | 0.94 | TLR2 (0.72) | TLR2CTSKMEN1MAPTKMT2A | |
| SCHEMBL19851664 | 0.94 | TLR2 (0.72) | TLR2CTSKMEN1MAPTKMT2A | |
| SCHEMBL19851534 | 0.92 | TLR2 (0.57) | TLR2CTSKMEN1MAPTKMT2A | |
| SCHEMBL19851496 | 0.89 | TLR2 (0.74) | TLR2CTSKCA1CA2 | |
| SCHEMBL19851520 | 0.89 | TLR2 (0.74) | TLR2CTSKCA1CA2 | |
| SCHEMBL19851705 | 0.89 | TLR2 (0.74) | TLR2CTSKCA1CA2 | |
| SCHEMBL19839674 | 0.88 | TLR2 (0.76) | TLR2MEN1KMT2ASIRT2SIRT1 | |
| SCHEMBL19839671 | 0.88 | TLR2 (0.76) | TLR2MEN1KMT2ASIRT2SIRT1 | |
| SCHEMBL28292702 | 0.86 | TLR2 (0.68) | TLR2MEN1KMT2ASIRT2SIRT1 | |
| SCHEMBL19839846 | 0.85 | TLR2 (0.81) | TLR2MEN1KMT2ASIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715167-A | Lipid-substituted amino 1, 2-and 1, 3-diol compounds as modulators of TLR2 dimerization | 神经孔疗法股份有限公司 | 2019-05-03 | — | — | CN | claimed |
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |