Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28315203 | 0.94 | CA1 (0.62) | CA1CA2CA9ACHEFFAR3 | |
| Bicarbonate SCHEMBL1482408 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29157215 | 0.89 | — | — | |
| Bicarbonate SCHEMBL168136 | 0.82 | — | — | |
| Bicarbonate SCHEMBL4437082 | 0.82 | — | — | |
| Bicarbonate SCHEMBL6905392 | 0.82 | — | — | |
| Bicarbonate SCHEMBL136536 | 0.82 | — | — | |
| Bicarbonate SCHEMBL166675 | 0.82 | — | — | |
| Bicarbonate SCHEMBL11308402 | 0.82 | CA1 (0.83) | CA1CA2CA9ACHEFFAR3 | |
| Bicarbonate SCHEMBL1280275 | 0.82 | CA1 (0.83) | CA1CA2CA9ACHEFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110416163-A | Picture pick-up device module, camera system, picture pick-up device encapsulation and manufacturing method | CANON KK | 2019-11-05 | — | — | CN | disclosed |
| CN-109716009-A | Stepped construction | 富士胶片株式会社 | 2019-05-03 | — | — | CN | disclosed |