Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921224 | 0.92 | ALDH1A1 (0.56) | HPGDALDH1A1USP2SIGMAR1BLM | |
| SCHEMBL7124360 | 0.88 | MEN1 (0.69) | ALDH1A1USP2TSHRPOLBCA12 | |
| SCHEMBL5546278 | 0.88 | POLB (0.69) | ALDH1A1USP2TSHRPOLBCA12 | |
| SCHEMBL252026 | 0.88 | HPGD (0.79) | HPGDALDH1A1USP2SIGMAR1BLM | |
| SCHEMBL7129676 | 0.88 | HPGD (0.79) | HPGDALDH1A1USP2SIGMAR1BLM | |
| Hydrochloric Acid SCHEMBL1597472 | 0.86 | HPGD (0.76) | HPGDALDH1A1USP2SIGMAR1BLM | |
| SCHEMBL4515670 | 0.84 | KDM4E (0.76) | ALDH1A1SIGMAR1TSHRCA12CA1 | |
| SCHEMBL743038 | 0.84 | HPGD (0.63) | HPGDALDH1A1USP2TSHRPOLB | |
| SCHEMBL161104 | 0.84 | HPGD (0.69) | HPGDALDH1A1USP2TSHRCA12 | |
| SCHEMBL3037345 | 0.83 | HSP90AA1 (0.49) | HPGDALDH1A1BLMPOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |