SCHEMBL28292947

SCHEMBL28292947

C=CC(=O)O[SiH2]N.C=CC(=O)O[SiH2]N

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.38
ALDH1A1 P00352 6/20 0.38
FGFR4 P22455 1/20 0.38
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28292922 1.00
SCHEMBL262019 0.77 TSHR (0.40) TSHRALDH1A1FGFR4TP53HIF1A
SCHEMBL6394406 0.74
SCHEMBL8733793 0.74
SCHEMBL18730301 0.72
SCHEMBL17329387 0.72
SCHEMBL28206807 0.72
SCHEMBL8994054 0.72
SCHEMBL4241797 0.72
SCHEMBL1591632 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105440068-B A kind of acryloxy amino silane and preparation method thereof 安徽硅宝有机硅新材料有限公司 2019-04-30 CN disclosed