Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718679 | 0.87 | ALDH1A1 (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1591632 | 0.84 | — | — | |
| SCHEMBL28824143 | 0.84 | — | — | |
| SCHEMBL13685616 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL8733793 | 0.79 | — | — | |
| SCHEMBL6394406 | 0.79 | — | — | |
| SCHEMBL28439987 | 0.78 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11764189 | 0.78 | — | — | |
| SCHEMBL8994054 | 0.77 | — | — | |
| SCHEMBL4241797 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520477-B1 | Inhibited acryloxysilanes and methacryloxysilanes | OSI SPECIALTIES INC (US) | 1997-03-05 | — | — | EP | claimed |
| EP-2033990-B2 | NITRILE RUBBER COMPOSITION, CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER | ZEON CORP (JP) | 2020-08-12 | — | — | EP | disclosed |
| US-9163132-B2 | Nitrile rubber composition, cross-linkable nitrile rubber composition and cross-linked rubber | ZEON CORPORATION (JP) | 2015-10-20 | — | — | US | disclosed |
| EP-2033990-B1 | NITRILE RUBBER COMPOSITION, CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER | ZEON CORP (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-8133948-B2 | Nitrile rubber composition, cross-linkable nitrile rubber composition and cross-linked rubber | ZEON CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20120041127-A1 | NITRILE RUBBER COMPOSITION, CROSS-LINKABLE NITRILE RUBBER COMPOSITION AND CROSS-LINKED RUBBER | NAGAMORI HIROYASU (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20090234054-A1 | NITRILE RUBBER COMPOSITION, CROSS-LINKABLE NITRILE RUBBER COMPOSITION AND CROSS-LINKED RUBBER | ZEON CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2033990-A1 | NITRILE RUBBER COMPOSITION, CROSSLINKABLE NITRILE RUBBER COMPOSITION AND CROSSLINKED RUBBER | ZEON CORPORATION (JP) | 2009-03-11 | — | — | EP | disclosed |