Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.62 |
| ▸ | AHCY | P23526 | 5/20 | 0.62 |
| ▸ | AMD1 | P17707 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.60 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.60 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.60 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.60 |
| ▸ | GAPDH | P04406 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
| ▸ | PI4KA | P42356 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832754 | 0.91 | EGFR (0.61) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL2828327 | 0.88 | AHCY (0.65) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL2115819 | 0.86 | EHMT1 (0.71) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL2829517 | 0.84 | EHMT1 (0.78) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL505376 | 0.84 | EGFR (0.71) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL2116140 | 0.83 | EGFR (0.65) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL10665708 | 0.83 | EHMT1 (0.70) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL1490898 | 0.83 | EGFR (0.71) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL30893122 | 0.82 | EGFR (0.84) | EGFRERBB2AHCYAMD1ADORA3 | |
| SCHEMBL5695357 | 0.82 | EGFR (0.84) | EGFRERBB2AHCYAMD1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874790-B1 | NEW S-ADENOSYL-L-METHIONINE ANALOGS WITH EXTENDED ACTIVATED GROUPS FOR TRANSFER BY METHYLTRANSFERASES | RWTH AACHEN (DE) | 2010-08-18 | — | — | EP | disclosed |
| EP-1712557-A1 | New s-adenosyl-L-methionine analogues with extended activated groups for transfer by methyltransferases | RWTH Aachen (DE) | 2006-10-18 | — | — | EP | disclosed |