⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605465 | 1.00 | — | — | |
| SCHEMBL28279241 | 0.98 | P2RX7 (0.57) | — | |
| Hydrochloric Acid SCHEMBL11797023 | 0.98 | P2RX7 (0.57) | — | |
| SCHEMBL22288333 | 0.98 | P2RX7 (0.57) | — | |
| SCHEMBL15956532 | 0.98 | P2RX7 (0.57) | — | |
| Formaldehyde SCHEMBL27859574 | 0.96 | P2RX7 (0.55) | — | |
| Acetic Acid SCHEMBL27708374 | 0.94 | P2RX7 (0.53) | — | |
| Trifluoroacetic Acid SCHEMBL30489000 | 0.88 | P2RX7 (0.49) | — | |
| Pyrrole SCHEMBL6111844 | 0.88 | P2RX7 (0.53) | — | |
| Piperazine SCHEMBL27529829 | 0.88 | P2RX7 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | claimed |
| EP-4646271-A1 | SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES | Mirati Therapeutics, Inc. (US) | 2025-11-12 | — | — | EP | claimed |
| CN-120072903-A | Composite positive electrode material of fast-charging sodium-ion battery and preparation method thereof | 浙江华宇钠电新能源科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120006268-A | Leadless high-phosphorus chemical nickel plating solution | 珠海联鼎化工设备有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| WO-2024148150-A1 | SUBSTITUTED SPIROCYCLIC-PYRROLOQUINAZOLINONES AND SPIROCYCLIC-PIPERIDINOQUINAZOLINONES | Mirati Therapeutics, Inc. (US) | 2024-07-11 | — | — | WO | claimed |
| EP-3551632-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | UNION THERAPEUTICS AS (DK) | 2024-06-12 | — | — | EP | claimed |
| CN-117510489-A | Dissolved coptisine type alkaloid quaternary ammonium salt and application thereof in preparing medicines | 中国医学科学院药物研究所 | 2024-02-06 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116554236-A | Cationic rare earth doped aluminum oxide cluster compound, and macro preparation method and application thereof | 闽都创新实验室 | 2023-08-08 | — | — | CN | claimed |
| EP-0701446-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-20 | — | — | EP | claimed |
| WO-1995011693-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-04 | — | — | WO | claimed |
| WO-1994027627-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0621788-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-02 | — | — | EP | claimed |
| CN-1077960-A | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1993-11-03 | — | — | CN | claimed |
| WO-1993013789-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | claimed |
| EP-0169144-B1 | PROCESS FOR THE PREPARATION OF 7-AMINO AND 7-SUBSTITUTED AMINO-DESACETOXYCEPHALOSPORINS FROM THE CORRESPONDING 6-SUBSTITUTED AMINO PENICILLIN SULPHOXIDES | GEMA S.A. (ES) | 1990-06-06 | — | — | EP | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| US-4623378-A | HYBRIIZATION OF PLANTS | CIBA-GEIGY CORPORATION (US) | 1986-11-18 | — | — | US | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |