Pyrrole

Pyrrole

SCHEMBL28293006

C=CCNC(=O)C=C.c1cc[nH]c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 4/20 0.40
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
TGM2 P21980 2/20 0.38
KMT2A Q03164 1/20 0.38
RAB9A P51151 3/20 0.38
NPC1 O15118 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.36
ZDHHC2 Q9UIJ5 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30851 0.85
Charcoal, Activated SCHEMBL890031 0.83
Ammonia Solution, Strong SCHEMBL1076016 0.83
Methane SCHEMBL27388128 0.83
SCHEMBL11874311 0.81 TSHR (0.56) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2
Dimethylamine SCHEMBL3821887 0.79 TSHR (0.54) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2
Trimethylammonium SCHEMBL28033781 0.77 TSHR (0.52) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2
Acrylamide SCHEMBL9362700 0.77 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2
SCHEMBL28287737 0.77 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
Glycolic Acid SCHEMBL9488455 0.75 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109663581-A A method of cobalt (II) ion blotting composite membrane is prepared with N- pyrrolidinyl acrylamide 昆明理工大学 2019-04-23 CN disclosed