Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23162638 | 0.98 | CSNK2A1 (0.66) | CSNK2A1MEN1LMNAKMT2AS1PR3 | |
| SCHEMBL3723071 | 0.84 | CSNK2A1 (0.45) | CSNK2A1MEN1LMNAKMT2AS1PR3 | |
| SCHEMBL3719650 | 0.84 | CSNK2A1 (0.45) | CSNK2A1MEN1LMNAKMT2AS1PR3 | |
| SCHEMBL1364967 | 0.79 | MAPT (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6215544 | 0.79 | CSNK2A1 (1.00) | CSNK2A1MEN1LMNAKMT2AS1PR3 | |
| SCHEMBL15711374 | 0.79 | CSNK2A1 (0.65) | CSNK2A1MEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3401585 | 0.78 | MAPT (0.53) | CSNK2A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL8388481 | 0.77 | POLB (0.57) | CSNK2A1LMNAS1PR3S1PR5KDM4E | |
| SCHEMBL1303622 | 0.77 | CSNK2A1 (0.40) | CSNK2A1MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL18994421 | 0.76 | MAPT (0.47) | CSNK2A1MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748885-A | A kind of preparation method of Ceritinib intermediate and Ceritinib | 新发药业有限公司 | 2019-05-14 | — | — | CN | disclosed |