Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719650 | 0.85 | CSNK2A1 (0.45) | CSNK2A1S1PR3S1PR5MAPTALDH1A1 | |
| SCHEMBL3721206 | 0.85 | HTT (0.35) | CSNK2A1MAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL28293124 | 0.84 | CSNK2A1 (0.65) | CSNK2A1S1PR3S1PR5MAPTALDH1A1 | |
| SCHEMBL21191017 | 0.83 | ALDH1A1 (0.34) | CSNK2A1MAPTALDH1A1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL23162638 | 0.82 | CSNK2A1 (0.66) | CSNK2A1S1PR3S1PR5MAPTALDH1A1 | |
| SCHEMBL30640901 | 0.81 | PDE4A (0.35) | MAPTALDH1A1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL21223997 | 0.81 | PDE4A (0.35) | MAPTALDH1A1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26291239 | 0.80 | CSNK2A1 (0.44) | CSNK2A1RXRARXRBRXRGP2RX3 | |
| SCHEMBL3718847 | 0.80 | CSNK2A1 (0.70) | CSNK2A1S1PR3ALDH1A1KDM4ELMNA | |
| SCHEMBL8712614 | 0.79 | ABL1 (0.42) | CSNK2A1S1PR3S1PR5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | CSNK2A1 1096/4885S1PR3 3426/4885S1PR5 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.