Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.95 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tectoquinone SCHEMBL29403487 | 0.98 | ELANE (1.00) | ELANEMAOAMAOBKMT2AMEN1 | |
| Tectoquinone SCHEMBL36822 | 0.98 | ELANE (1.00) | ELANEMAOAMAOBKMT2AMEN1 | |
| Tectoquinone SCHEMBL28051910 | 0.98 | ELANE (1.00) | ELANEMAOAMAOBKMT2AMEN1 | |
| Tectoquinone SCHEMBL30618448 | 0.98 | ELANE (1.00) | ELANEMAOAMAOBKMT2AMEN1 | |
| Tectoquinone SCHEMBL2444159 | 0.98 | ELANE (1.00) | ELANEMAOAMAOBKMT2AMEN1 | |
| SCHEMBL30419213 | 0.95 | ELANE (0.95) | ELANEMAOAMAOBKMT2AMEN1 | |
| SCHEMBL354335 | 0.95 | ELANE (0.95) | ELANEMAOAMAOBKMT2AMEN1 | |
| SCHEMBL15450608 | 0.91 | ELANE (0.88) | ELANEMAOAMAOBKMT2AMEN1 | |
| SCHEMBL6036732 | 0.91 | ELANE (0.87) | ELANEMAOAMAOBKMT2AMEN1 | |
| SCHEMBL546782 | 0.91 | ELANE (0.87) | ELANEMAOAMAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748810-A | 2-aminomethyl-9, 10-anthraquinone derivative, preparation method and application thereof | 上海医药工业研究院 | 2019-05-14 | — | — | CN | claimed |
| CN-109748810-A | 2-aminomethyl-9, 10-anthraquinone derivative, preparation method and application thereof | 上海医药工业研究院 | 2019-05-14 | — | — | CN | disclosed |
| CN-109748810-A | 2-aminomethyl-9, 10-anthraquinone derivative, preparation method and application thereof | 上海医药工业研究院 | 2019-05-14 | — | — | CN | disclosed |
| CN-109748810-A | 2-aminomethyl-9, 10-anthraquinone derivative, preparation method and application thereof | 上海医药工业研究院 | 2019-05-14 | — | — | CN | disclosed |