SCHEMBL546782

SCHEMBL546782

Cc1ccc2c(c1)-c1ccccc1C2=O

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.87
MAOA P21397 2/20 0.61
MAOB P27338 1/20 0.61
KMT2A Q03164 5/20 0.55
MEN1 O00255 4/20 0.55
CDC25B P30305 1/20 0.55
SMN1; SMN2 Q16637 7/20 0.52
MAPT P10636 6/20 0.52
RAB9A P51151 6/20 0.52
NPC1 O15118 5/20 0.52
MAPK1 P28482 4/20 0.52
HTT P42858 3/20 0.52
LMNA P02545 3/20 0.52
PTPRC P08575 2/20 0.52
APAF1 O14727 2/20 0.52
POLB P06746 2/20 0.52
THRB P10828 2/20 0.52
S100A4 P26447 2/20 0.52
GALK1 P51570 2/20 0.52
BLM P54132 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899750 1.00 ELANE (0.87) ELANEMAOAMAOBKMT2AMEN1
SCHEMBL16656188 0.95 ELANE (0.79) ELANEMAOAMAOBKMT2AMEN1
SCHEMBL354335 0.95 ELANE (0.95) ELANEMAOAMAOBKMT2AMEN1
SCHEMBL30419213 0.95 ELANE (0.95) ELANEMAOAMAOBKMT2AMEN1
Tectoquinone SCHEMBL36822 0.93 ELANE (1.00) ELANEMAOAMAOBKMT2AMEN1
Tectoquinone SCHEMBL2444159 0.93 ELANE (1.00) ELANEMAOAMAOBKMT2AMEN1
Tectoquinone SCHEMBL29403487 0.93 ELANE (1.00) ELANEMAOAMAOBKMT2AMEN1
Tectoquinone SCHEMBL30618448 0.93 ELANE (1.00) ELANEMAOAMAOBKMT2AMEN1
Tectoquinone SCHEMBL28051910 0.93 ELANE (1.00) ELANEMAOAMAOBKMT2AMEN1
SCHEMBL6036732 0.91 ELANE (0.87) ELANEMAOAMAOBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115528215-A Secondary battery positive electrode material pre-ionization reagent and preparation method and application thereof 深圳珈钠能源科技有限公司 2022-12-27 CN claimed
US-20240360319-A1 SUBSTITUTED POLYFLUORENE COMPOUNDS BioLegend, Inc. 2024-10-31 US disclosed
US-12091554-B2 Substituted polyfluorene compounds BioLegend, Inc. (US) 2024-09-17 US disclosed
CN-113365971-B Compound and light-emitting element using same 住友化学株式会社 2024-04-30 CN disclosed
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
US-11917913-B2 Substituted oxepines MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
US-20230002555-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM FORMING COMPOSITION CONTAINING SAME NISSAN CHEMICAL CORPORATION (JP) 2023-01-05 US disclosed
CN-115528215-A Secondary battery positive electrode material pre-ionization reagent and preparation method and application thereof 深圳珈钠能源科技有限公司 2022-12-27 CN disclosed
CN-113652705-B Method for synthesizing fluorenone through catalytic electrolysis of N-hydroxyphthalimide 北京工业大学 2022-07-22 CN disclosed
US-20220123220-A1 COMPOUND AND LIGHT EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-04-21 US disclosed
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-08-21 US disclosed
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-08-21 US disclosed
US-20080194590-A1 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors PFIZER INC 2008-08-14 US disclosed
US-7399577-B2 Halogenated oxime derivatives and the use thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-07-15 US disclosed
US-7399577-B2 Halogenated oxime derivatives and the use thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-07-15 US disclosed
US-20070059364-A1 Active substance combination comprising a compound with npy receptor affinity and a compound with 5-ht6 receptor affinity LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2007-03-15 US disclosed
US-20070059364-A1 Active substance combination comprising a compound with npy receptor affinity and a compound with 5-ht6 receptor affinity LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2007-03-15 US disclosed
WO-2001009117-A1 TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS ALLELLIX NEUROSCIENCE INC. (US) 2001-02-08 WO disclosed
US-6162824-A NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS ALLELIX NEUROSCIENCE INC. 2000-12-19 US disclosed
EP-0886182-A1 Positive photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME LEF1, FMNL1, AFF1 ELANE 767/4885MAOA 717/4885MAOB 924/4885
US-20070059364-A1 Active substance combination comprising a compound with npy receptor affinity and a compound with 5-ht6 receptor affinity HTR6, NPY5R, NPY2R ELANE 2736/4885MAOA 136/4885MAOB 197/4885
US-11917913-B2 Substituted oxepines OXGR1, OXTR, OCIAD2 ELANE 1010/4885MAOA 161/4885MAOB 446/4885
US-20220123220-A1 COMPOUND AND LIGHT EMITTING ELEMENT USING SAME NR2E3, CRY1, GRK1 ELANE 974/4885MAOA 1391/4885MAOB 1620/4885
US-20080194590-A1 4-Piperazinylthieno [2,3-D] Pyrimidine Compounds as Platelet Aggregation Inhibitors PFKP, PF4, P2RY4 ELANE 1923/4885MAOA 1106/4885MAOB 1020/4885
US-20240360319-A1 SUBSTITUTED POLYFLUORENE COMPOUNDS PARG, PFAS, PARN ELANE 1023/4885MAOA 1268/4885MAOB 1458/4885
US-12091554-B2 Substituted polyfluorene compounds PARG, PFAS, PARN ELANE 1023/4885MAOA 1268/4885MAOB 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.