Aziridine

Aziridine

SCHEMBL28293180

C1CN1.CCCCCCCCCCCCCCCCCC

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
THRB P10828 1/20 0.61
GNAI3 P08754 7/20 0.50
GNAO1 P09471 7/20 0.50
GNAI1 P63096 7/20 0.50
DNM1 Q05193 5/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SLC22A1 O15245 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL28830202 1.00 TSHR (0.61) TSHRTHRBGNAI3GNAO1GNAI1
Nonane SCHEMBL27394311 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Heptane SCHEMBL27336545 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Decane SCHEMBL28285911 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Octane SCHEMBL11308877 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Tetradecane SCHEMBL27500186 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Nonane SCHEMBL10873465 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Decane SCHEMBL27463252 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Tridecane SCHEMBL27396019 0.96 TSHR (0.57) TSHRTHRBGNAI3GNAO1GNAI1
Hexane SCHEMBL28193361 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109786721-A A kind of positive electrode, and its preparation method and application 中科廊坊过程工程研究院 2019-05-21 CN claimed
CN-109786721-A A kind of positive electrode, and its preparation method and application 中科廊坊过程工程研究院 2019-05-21 CN disclosed