SCHEMBL28293190

SCHEMBL28293190

FC(F)COCCc1ccc[nH]1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11216376 0.82 MAOA (0.36) DRD2DRD4DRD3MAOA
SCHEMBL30693096 0.76 MAOA (0.36) DRD2DRD4DRD3MAOA
SCHEMBL7948046 0.73 MAOA (0.34) MAOA
SCHEMBL11117749 0.71 HRH4 (0.49)
SCHEMBL1244574 0.71 TSHR (0.41)
SCHEMBL13531936 0.71
SCHEMBL7518065 0.71
SCHEMBL7172295 0.71 MAOA (0.42) DRD2DRD4DRD3MAOA
SCHEMBL30166009 0.70
SCHEMBL28043570 0.69 MAOA (0.37) DRD2DRD4DRD3MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074874-B ERK inhibitor 伊莱利利公司 2019-04-23 CN disclosed