Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651848 | 0.88 | TSHR (0.62) | TSHRLMNATHRAMAPTPOLB | |
| SCHEMBL10918542 | 0.88 | TSHR (0.71) | TSHRGAALMNATHRAMAPT | |
| SCHEMBL20495254 | 0.87 | TSHR (0.57) | TSHRGAALMNAMAPTPOLB | |
| SCHEMBL29864638 | 0.86 | TSHR (0.65) | TSHRLMNATHRAMAPTCYP19A1 | |
| SCHEMBL5250015 | 0.86 | TSHR (0.65) | TSHRLMNATHRAMAPTCYP19A1 | |
| SCHEMBL24622615 | 0.83 | ALDH1A1 (0.58) | TSHRLMNATHRAMAPTPOLB | |
| SCHEMBL29768852 | 0.83 | ALDH1A1 (0.58) | TSHRLMNATHRAMAPTPOLB | |
| SCHEMBL1644518 | 0.82 | POLB (0.63) | TSHRLMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL11190287 | 0.82 | TSHR (0.56) | TSHRLMNATHRACYP19A1CYP1A2 | |
| SCHEMBL3791727 | 0.81 | PELI1 (0.52) | TSHRGAATHRAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641836-A | Fluorinated 2- amino -4- (substituted amino) carbanilate derivative | 赛弗卢尔生命科学公司 | 2019-04-16 | — | — | CN | disclosed |