SCHEMBL28293314

SCHEMBL28293314

Cc1cccc(S(C)(=O)=O)c1-c1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.46
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 2/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
MYC P01106 1/20 0.41
ELANE P08246 2/20 0.41
CTSG P08311 1/20 0.41
MAOA P21397 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CA12 O43570 1/20 0.40
CDK2 P24941 1/20 0.40
ATM Q13315 2/20 0.39
TRPA1 O75762 3/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.39
MAPK1 P28482 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7865651 0.87 STAT3 (0.46) STAT3MEN1KMT2AGAAESR1
SCHEMBL3823915 0.81 STAT3 (0.47) STAT3MYCCA1CA2CA9
SCHEMBL6530985 0.80 MYC (0.53) MEN1KMT2AGAAMYCELANE
SCHEMBL7583763 0.78 TRPA1 (0.50) MEN1KMT2AGAAMYCELANE
SCHEMBL30535832 0.78 TRPA1 (0.50) MEN1KMT2AGAAMYCELANE
SCHEMBL27957398 0.77 STAT3 (0.63) STAT3MEN1KMT2AGAAESR1
SCHEMBL7868085 0.77 STAT3 (0.50) STAT3MEN1KMT2AGAAESR1
SCHEMBL23202746 0.76 TRPA1 (0.48) MEN1KMT2AGAAMYCELANE
SCHEMBL28115904 0.76 TRPA1 (0.48) MEN1KMT2AGAAMYCELANE
Hydrochloric Acid SCHEMBL5808141 0.74 CA1 (0.51) STAT3MYCCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776620-A A kind of metallocene complex and its preparation and application 上海东化环境工程有限公司 2019-05-21 CN disclosed