Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831363 | 0.78 | KDM1A (0.56) | KDM1AMAOARCOR1MEN1KMT2A | |
| SCHEMBL7170567 | 0.78 | KDM1A (0.48) | KDM1AMAOARCOR1MEN1KMT2A | |
| SCHEMBL28460969 | 0.76 | KDM1A (0.47) | KDM1AMAOARCOR1MEN1KMT2A | |
| SCHEMBL10975824 | 0.76 | POLB (0.43) | MEN1KMT2ANPC1RAB9ACYP2C19 | |
| SCHEMBL8791569 | 0.73 | KDM1A (0.52) | KDM1AMAOARCOR1MEN1KMT2A | |
| SCHEMBL19788743 | 0.72 | P2RX4 (0.46) | KDM1AMAOARCOR1MEN1KMT2A | |
| SCHEMBL5241641 | 0.71 | KDM1A (0.46) | KDM1AMAOARCOR1MEN1KMT2A | |
| SCHEMBL2530349 | 0.70 | ALDH1A1 (0.50) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL22675703 | 0.68 | ALDH1A1 (0.55) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL20628724 | 0.68 | NR1H2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674222-B | A kind of chiral tricyclic ketone amine compound and its synthetic method and application | 华东师范大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-106674222-A | Chiral tricyclic keto-amine compound as well as synthetic method and application thereof | 华东师范大学 | 2017-05-17 | — | — | CN | disclosed |