Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.30 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010793 | 0.84 | ST14 (0.51) | ST14 | |
| SCHEMBL14756813 | 0.71 | TAAR1 (0.42) | CYP2A6PNMTGAA | |
| SCHEMBL7699218 | 0.68 | HRH3 (0.37) | ST14HRH3CA12CA1CA2 | |
| SCHEMBL30523718 | 0.68 | HRH3 (0.37) | ST14HRH3CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL31165140 | 0.67 | RAD52 (0.39) | HRH3CA12CA1CA2CA3 | |
| SCHEMBL3047306 | 0.64 | TAAR1 (0.34) | ST14HRH3CA12CA1CA2 | |
| SCHEMBL8007552 | 0.63 | PDE4A (0.50) | — | |
| SCHEMBL5504129 | 0.63 | KMT2A (0.47) | HRH3CA12CA1CA2CA7 | |
| SCHEMBL29673223 | 0.61 | KMT2A (0.50) | CA12CA1CA2CA7CA14 | |
| SCHEMBL5957796 | 0.61 | KMT2A (0.46) | HRH3CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641892-A | 2- oxo-imidazol as reversible BTK inhibitor and pyridine and application thereof | 默克专利有限公司 | 2019-04-16 | — | — | CN | disclosed |