Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.39 |
| ▸ | MMP9 | P14780 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 5/20 | 0.39 |
| ▸ | MMP14 | P50281 | 5/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 7/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748451 | 0.92 | ST14 (0.42) | ST14MAOB | |
| SCHEMBL28293446 | 0.84 | ST14 (0.34) | ST14 | |
| SCHEMBL19622266 | 0.83 | ALDH1A1 (0.47) | MAOB | |
| SCHEMBL5801556 | 0.81 | PDE4A (0.49) | MAOB | |
| SCHEMBL14748454 | 0.81 | MAOB (0.53) | MAOB | |
| SCHEMBL8007552 | 0.80 | PDE4A (0.50) | MAOB | |
| SCHEMBL8007094 | 0.80 | PDE4A (0.50) | MMP2MMP9MMP14MAOB | |
| SCHEMBL14748434 | 0.80 | PDE4A (0.50) | MAOB | |
| SCHEMBL7995257 | 0.78 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL14470676 | 0.76 | PDE4B (0.53) | MMP8MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |