Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 3/20 | 0.34 |
| ▸ | ARG1 | P05089 | 3/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28256845 | 0.95 | PRCP (0.35) | KMT2AARG1ARG2PRCPS1PR2 | |
| Hydrochloric Acid SCHEMBL28256875 | 0.95 | PRCP (0.35) | KMT2AARG1ARG2PRCPS1PR2 | |
| Hydrochloric Acid SCHEMBL28256846 | 0.95 | PRCP (0.35) | KMT2AARG1ARG2PRCPS1PR2 | |
| Acetic Acid SCHEMBL29252195 | 0.77 | S1PR1 (0.46) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL293993 | 0.74 | HRH3 (0.45) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL27534493 | 0.73 | FDPS (0.46) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL29449286 | 0.72 | S1PR1 (0.45) | KMT2AMEN1LMNATP53PRCP | |
| SCHEMBL7303522 | 0.72 | S1PR1 (0.45) | KMT2AMEN1LMNATP53PRCP | |
| SCHEMBL6050340 | 0.72 | CYP1A2 (0.46) | FDPSKMT2AMEN1LMNATP53 | |
| SCHEMBL3224559 | 0.72 | CYP1A2 (0.46) | FDPSKMT2AMEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110123820-A | Arginase inhibitor and its application method | 阿斯利康公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-104857005-B | Arginase inhibitor and its application method | 阿斯利康公司 | 2019-04-26 | — | — | CN | disclosed |