SCHEMBL28293594

SCHEMBL28293594

CC1=CN(CCC(=O)O)CC(CO)=C1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.34
KDM4E B2RXH2 3/20 0.32
POLB P06746 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
EGLN3 Q9H6Z9 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28283735 0.86 ALDH1A1 (0.34) ALDH1A1PKMMAPK1KDM4EPOLB
Hydrochloric Acid SCHEMBL6439106 0.64 HTT (0.33) ALDH1A1KDM4EPOLBMAPT
SCHEMBL6791494 0.59 GLA (0.39) ALDH1A1PKMMAPK1KDM4EPOLB
SCHEMBL574725 0.58 CYP1A2 (0.35) ALDH1A1PKMMAPK1KDM4EPOLB
Hydrochloric Acid SCHEMBL28462903 0.57 GLA (0.37) ALDH1A1PKMMAPK1KDM4EPOLB
Bromide SCHEMBL571257 0.57 CYP1A2 (0.34) ALDH1A1PKMMAPK1KDM4EPOLB
SCHEMBL7396846 0.56 MAPK1 (0.53) ALDH1A1PKMMAPK1KDM4EPOLB
SCHEMBL27941128 0.54 GLA (0.34) ALDH1A1PKMMAPK1KDM4EPOLB
Alcohol SCHEMBL28379053 0.54 GLA (0.57) ALDH1A1PKMMAPK1POLBL3MBTL1
Alcohol SCHEMBL5801058 0.54 GLA (0.57) ALDH1A1PKMMAPK1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608438-A The preparation method of midbody compound, preparation method and application and Rupatadine fumarate impurity J 杭州澳医保灵药业有限公司 2019-04-12 CN disclosed