Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | VNN1 | O95497 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993717 | 0.84 | LTA4H (0.60) | MEN1MAPTKMT2AVNN1LTA4H | |
| SCHEMBL112756 | 0.81 | HSD17B10 (0.50) | MEN1MAPTKMT2AP2RX7ALDH1A1 | |
| SCHEMBL17873926 | 0.78 | LTA4H (0.60) | MEN1MAPTKMT2AVNN1LTA4H | |
| SCHEMBL12086902 | 0.77 | IDO1 (0.56) | MEN1MAPTKMT2ALTA4HCYP1A2 | |
| SCHEMBL4346359 | 0.75 | BRD4 (0.49) | P2RX7CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL10557452 | 0.75 | POLB (0.66) | MEN1MAPTKMT2ALTA4HCYP1A2 | |
| SCHEMBL7423961 | 0.74 | MAPT (0.59) | MEN1MAPTKMT2AVNN1LTA4H | |
| SCHEMBL1030471 | 0.73 | KMT2A (0.51) | MEN1MAPTKMT2ALTA4HCYP1A2 | |
| SCHEMBL10559382 | 0.72 | KDM4E (0.71) | MEN1KMT2AVNN1LTA4HALDH1A1 | |
| SCHEMBL10559807 | 0.72 | LTA4H (0.60) | MEN1MAPTKMT2AVNN1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045552-B | Medicinal compound as neuroprotective agent | 江苏先声药业有限公司 | 2019-06-11 | — | — | CN | disclosed |