Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776229 | 0.92 | MAPT (0.61) | TSHRHSD17B10KMT2ATAAR1FAAH | |
| SCHEMBL28108051 | 0.90 | MLNR (0.53) | TSHRHSD17B10MAPTCA1CA2 | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.85 | TSHR (0.68) | TSHRHSD17B10KMT2AFAAHPRSS1 | |
| SCHEMBL22662767 | 0.84 | AR (0.64) | KMT2AALDH1A1CA1CA2CA5A | |
| Benzylsulfonylbenzene SCHEMBL1877584 | 0.83 | TSHR (0.66) | TSHRHSD17B10KMT2AFAAHPRSS1 | |
| SCHEMBL28226562 | 0.81 | HSD17B10 (0.46) | TSHRHSD17B10KMT2ATAAR1MAPT | |
| SCHEMBL4772848 | 0.81 | PSEN1 (0.63) | KMT2AMAPTALDH1A1 | |
| SCHEMBL2922447 | 0.81 | POLB (0.49) | TSHRHSD17B10KMT2AMAPTCA1 | |
| SCHEMBL22662755 | 0.81 | POLB (0.56) | TSHRHSD17B10KMT2AMAPTALDH1A1 | |
| SCHEMBL20002876 | 0.81 | ACHE (0.58) | KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | claimed |
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | claimed |
| CN-109761863-B | (E) - (2- (phenylsulfonyl) ethenyl) benzene and its derivative and synthetic method | 湘潭大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-109761863-A | (E)-(2-(phenyl sulfonyl) vinyl) benzene and its derivative and synthetic method | 湘潭大学 | 2019-05-17 | — | — | CN | disclosed |