Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688680 | 0.83 | MEN1 (0.45) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL6285466 | 0.83 | CYP3A4 (0.45) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| Charcoal, Activated SCHEMBL9345982 | 0.82 | CYP3A4 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL28204604 | 0.82 | CD38 (0.45) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27960762 | 0.80 | MEN1 (0.43) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL31411999 | 0.80 | MEN1 (0.43) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL3807642 | 0.79 | BID (0.47) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL4351825 | 0.79 | BID (0.47) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL22736732 | 0.79 | BID (0.48) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL27792190 | 0.79 | MEN1 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651179-A | 2- (2- amino benzoyl) benzoic acid derivative and preparation method thereof | 厦门华厦学院 | 2019-04-19 | — | — | CN | disclosed |