Anisole

Anisole

SCHEMBL28293679

COc1ccccc1.Cn1cnc2cncnc21

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 13/20 0.48
CYP3A4 P08684 12/20 0.48
USP2 O75604 9/20 0.48
CYP2C19 P33261 9/20 0.48
CYP2D6 P10635 4/20 0.48
MAPK1 P28482 1/20 0.48
GRM5 P41594 2/20 0.48
CASP1 P29466 2/20 0.47
CASP7 P55210 2/20 0.47
LTA4H P09960 1/20 0.47
CYP2C9 P11712 9/20 0.46
ALDH1A1 P00352 9/20 0.46
TSHR P16473 7/20 0.46
LMNA P02545 5/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
CLK4 Q9HAZ1 3/20 0.46
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 2/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30341176 0.82 GRM5 (0.46) CYP1A2CYP3A4USP2CYP2C19MAPK1
SCHEMBL256372 0.82 GRM5 (0.46) CYP1A2CYP3A4USP2CYP2C19MAPK1
Benzamide SCHEMBL27825323 0.76 GRM5 (0.51) CYP1A2CYP3A4CYP2C19GRM5LTA4H
SCHEMBL28195658 0.71 HDAC1 (0.58) CYP1A2CYP3A4USP2CYP2C19CYP2D6
SCHEMBL27485126 0.71 CYP3A4 (0.45) CYP1A2CYP3A4USP2CYP2C19CYP2D6
SCHEMBL14820091 0.71 GRM5 (0.54) GRM5EGFR
SCHEMBL1398869 0.69 FDPS (0.41) CYP1A2CYP3A4USP2CYP2C19CYP2D6
SCHEMBL680855 0.68 FGFR1 (0.56) CYP1A2CYP3A4USP2CYP2C19MAPK1
Hydrochloric Acid SCHEMBL4456679 0.67 FGFR1 (0.54) CYP1A2CYP3A4USP2CYP2C19MAPK1
SCHEMBL16012870 0.66 CYP3A4 (0.54) CYP1A2CYP3A4USP2CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651370-A A kind of purine analog derivative free radical precursor molecule and preparation method thereof 桂林理工大学 2019-04-19 CN disclosed