Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463761 | 1.00 | ALDH1A1 (0.57) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL4638474 | 0.93 | MAPK1 (0.56) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL4163008 | 0.92 | MAPK1 (0.63) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL11281767 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL27685761 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL11806576 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL1883666 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL4684378 | 0.84 | CNR2 (0.49) | MAPTKMT2ALMNA | |
| SCHEMBL2394373 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 | |
| Bromide SCHEMBL10998875 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTCYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170847-B | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-109796351-B | Novel preparation method of drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2021-08-17 | — | — | CN | claimed |
| CN-111170847-A | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2020-05-19 | — | — | CN | claimed |
| CN-109796351-A | A kind of novel preparation method of drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-111170847-B | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-111170847-B | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-109796351-B | Novel preparation method of drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-109796351-B | Novel preparation method of drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111170847-A | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-111170847-A | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-109796351-A | A kind of novel preparation method of drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2019-05-24 | — | — | CN | disclosed |