SCHEMBL28293889

SCHEMBL28293889

CCCC(C(=O)O)C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
TDP1 Q9NUW8 3/20 0.49
MAPK1 P28482 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KMT2A Q03164 1/20 0.49
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CTSK P43235 1/20 0.46
MMP8 P22894 1/20 0.45
CTSB P07858 1/20 0.45
LMNA P02545 1/20 0.45
HCAR2 Q8TDS4 1/20 0.45
CTSL P07711 1/20 0.44
CTSS P25774 1/20 0.44
POLB P06746 1/20 0.44
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19105243 0.95 ALDH1A1 (0.56) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL7322089 0.90 ALDH1A1 (0.54) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL7642669 0.90 ALDH1A1 (0.56) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL28274065 0.89 ALDH1A1 (0.50) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL28556815 0.89 ALDH1A1 (0.52) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL28123750 0.86 ALDH1A1 (0.47) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL7391865 0.86 ALDH1A1 (0.58) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL14873821 0.86 ALDH1A1 (0.58) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL19105272 0.85 ALDH1A1 (0.55) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4
SCHEMBL11636918 0.84 CA1 (0.63) ALDH1A1TDP1MAPK1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109678997-A Catalytic component and catalyst and pre-polymerized catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2019-04-26 CN disclosed