Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 9/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450433 | 0.87 | RXRA (0.66) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL6450432 | 0.87 | RXRA (0.66) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL1619112 | 0.79 | RXRA (0.69) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL304434 | 0.79 | RXRA (0.69) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL304433 | 0.79 | RXRA (0.69) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL14492768 | 0.77 | RXRA (0.57) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL5484611 | 0.77 | RXRA (0.57) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL5484607 | 0.77 | RXRA (0.57) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL5757584 | 0.77 | RXRA (0.63) | SCN9ARXRAPIM1PIM2TTR | |
| SCHEMBL5791119 | 0.77 | RXRA (0.63) | SCN9ARXRAPIM1PIM2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715637-A | Glucokinase activators and its application method | 百时美施贵宝公司 | 2019-05-03 | — | — | CN | disclosed |