Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.81 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.71 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | MC4R | P32245 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.67 |
| ▸ | MC3R | P41968 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153896 | 1.00 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL3705430 | 1.00 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL7153891 | 1.00 | SLC2A1 (0.81) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL10873061 | 0.97 | SLC2A1 (0.78) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL10873052 | 0.97 | SLC2A1 (0.78) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL10433618 | 0.97 | SLC2A1 (0.78) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL10772483 | 0.91 | SLC2A1 (0.83) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL10772479 | 0.91 | SLC2A1 (0.83) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL10775119 | 0.91 | SLC2A1 (0.97) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 | |
| SCHEMBL11182206 | 0.91 | SLC2A1 (0.83) | SLC2A1ADRB2ADRB3ADRB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715637-A | Glucokinase activators and its application method | 百时美施贵宝公司 | 2019-05-03 | — | — | CN | disclosed |