Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GALR1 | P47211 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617015 | 0.86 | TP53 (0.62) | TP53POLBHPGDMAPTGALR1 | |
| SCHEMBL4193217 | 0.85 | TP53 (0.61) | TP53POLBHPGDGALR1 | |
| SCHEMBL7871362 | 0.84 | KAT6A (0.48) | CHEK2MEN1USP2MAPTALOX15 | |
| SCHEMBL1697936 | 0.84 | CA12 (0.54) | — | |
| SCHEMBL6705545 | 0.82 | MAPT (0.55) | CHEK2HPGDMEN1USP2MAPT | |
| SCHEMBL2404818 | 0.82 | NPC1 (0.59) | TP53POLBHPGDMAPT | |
| SCHEMBL5863201 | 0.80 | TP53 (0.57) | TP53POLBHPGDGALR1 | |
| SCHEMBL11223090 | 0.80 | TP53 (0.59) | TP53POLBHPGDMAPTKMT2A | |
| SCHEMBL2265211 | 0.79 | IMPDH2 (0.57) | TP53POLBHPGD | |
| SCHEMBL5863231 | 0.79 | TP53 (0.56) | TP53POLBHPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |