Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22714090 | 0.83 | MAPT (0.62) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL934433 | 0.81 | GAA (0.61) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL933860 | 0.80 | MEN1 (0.69) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL31213412 | 0.79 | SMN1; SMN2 (0.54) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL3817302 | 0.79 | MEN1 (0.54) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL29420482 | 0.79 | SMN1; SMN2 (0.54) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL29420504 | 0.79 | MAPT (0.59) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL1013028 | 0.79 | KMT2A (0.49) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL23817280 | 0.76 | NPC1 (0.57) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL2905312 | 0.76 | MAPT (0.53) | MEN1KMT2AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651376-A | A kind of synthetic method of azatropylidene simultaneously [5,4,3-cd] indoles -6- ketone compound | 江苏创诺制药有限公司 | 2019-04-19 | — | — | CN | disclosed |