SCHEMBL934433

SCHEMBL934433

c1ccc(NN=C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.61
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
ALDH1A1 P00352 7/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
HPGD P15428 2/20 0.51
ALOX12 P18054 1/20 0.51
RAB9A P51151 4/20 0.49
HNF4A P41235 1/20 0.48
MAPT P10636 5/20 0.44
BCHE P06276 1/20 0.43
KDM4E B2RXH2 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
TAAR1 Q96RJ0 1/20 0.42
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
CYP1A1 P04798 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11986720 0.89 GAA (0.51) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL31213417 0.88 GAA (0.51) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL9451221 0.87 KMT2A (0.63) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL18672224 0.87 GAA (0.63) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL29420498 0.86 MEN1 (0.49) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL933860 0.86 MEN1 (0.69) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL935280 0.86 CTSL (0.56) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL3818727 0.86 MAPT (0.56) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL31213415 0.84 SMN1; SMN2 (0.51) GAAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL31213402 0.84 MAPT (0.63) GAAMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7557248-B2 Method of forming a carbon-heteroatom bond RHODIA CHIMIE (FR) 2009-07-07 US claimed
US-20070243999-A1 Method of Forming a Carbon-Heteroatom Bond RHODIA CHIMIE (FR) 2007-10-18 US claimed
US-4410457-A EPOXY REACTIVE SOLVENT, EPOXY RESIN, LATENT HARDENER, EPOXIDE-DIALKYLAMINE ADDUCT SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-18 US claimed
CN-118880357-A Benzoxazine derivative and electrochemical synthesis method thereof 齐齐哈尔医学院 2024-11-01 CN disclosed
CN-114195676-B Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs 广州药本君安医药科技股份有限公司 2022-08-05 CN disclosed
CN-114195676-A Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs 广州药本君安医药科技股份有限公司 2022-03-18 CN disclosed
US-9983218-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2018-05-29 US disclosed
US-9960359-B2 Arylamine-based compound and organic light emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed
US-9960359-B2 Arylamine-based compound and organic light emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed
US-20180024144-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF ABBVIE INC. (US) 2018-01-25 US disclosed
US-9625475-B2 Indole and indoline derivatives and methods of use thereof ABBVIE INC. (US) 2017-04-18 US disclosed
WO-1998058649-A1 SALT COMPLEX FOR LYMPHATIC DELIVERY DEKK-TEC, INC. (US) 1998-12-30 WO disclosed
EP-0502992-A4 CONDUCTIVE ADHESIVE USEFUL FOR BONDING A SEMICONDUCTOR DIE TO A CONDUCTIVE SUPPORT BASE 1993-05-26 EP disclosed
EP-0502992-A1 CONDUCTIVE ADHESIVE USEFUL FOR BONDING A SEMICONDUCTOR DIE TO A CONDUCTIVE SUPPORT BASE ACHESON INDUSTRIES, INC. (US) 1992-09-16 EP disclosed
US-5043102-A Blend of epoxy resin, unsaturated monomer, free radical catalyst, and silver particles ADVANCED PRODUCTS, INC. (US) 1991-08-27 US disclosed
WO-1991008575-A1 CONDUCTIVE ADHESIVE USEFUL FOR BONDING A SEMICONDUCTOR DIE TO A CONDUCTIVE SUPPORT BASE ADVANCED PRODUCTS, INC. (US) 1991-06-13 WO disclosed
EP-0039230-B1 CURABLE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-11 EP disclosed
US-4410457-A EPOXY REACTIVE SOLVENT, EPOXY RESIN, LATENT HARDENER, EPOXIDE-DIALKYLAMINE ADDUCT SUMITOMO CHEMICAL CO., LTD. (JP) 1983-10-18 US disclosed
US-4360649-A EPOXY RESIN, EPOXIDE-DIALKYLAMINE ADDUCT, UREA COMPOUND, CURING AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-23 US disclosed
EP-0039230-A2 Curable composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180024144-A1 INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF IDO1, IDO2, TPH1 GAA 3876/4885MEN1 1382/4885KMT2A 2036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.