Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27903707 | 0.86 | TDP1 (0.39) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27844874 | 0.86 | TDP1 (0.39) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27919819 | 0.86 | TDP1 (0.39) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27658298 | 0.86 | TDP1 (0.39) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27655747 | 0.86 | TDP1 (0.39) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27522712 | 0.86 | TDP1 (0.39) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27737964 | 0.86 | TDP1 (0.39) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27655720 | 0.85 | CHRNB2 (0.40) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL28829623 | 0.85 | TDP1 (0.38) | TDP1EEDKMT2ACPN1CPB2 | |
| Tert-Butyl Formate SCHEMBL27886873 | 0.85 | TDP1 (0.38) | TDP1EEDKMT2ACPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776522-A | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-05-21 | — | — | CN | disclosed |