Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849440 | 0.86 | TSHR (0.53) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL11853743 | 0.85 | MAPK1 (0.54) | HSD17B2TSHRLMNACYP3A4HPGD | |
| SCHEMBL7828549 | 0.83 | CA12 (0.51) | HSD17B2CA12CA1CA2CA4 | |
| SCHEMBL13554532 | 0.82 | CYP3A4 (0.63) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL5960635 | 0.82 | HSD17B2 (0.51) | HSD17B2PKMTSHRLMNACYP3A4 | |
| SCHEMBL11854718 | 0.82 | CA12 (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL26437234 | 0.81 | LMNA (0.54) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL5232483 | 0.81 | HPGD (0.49) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL7241195 | 0.80 | CYP3A4 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9515990 | 0.79 | CA1 (0.69) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404372-B1 | PHARMACEUTICAL FORMULATIONS AND LIGANDS FOR USE THEREIN; MIMETICS FOR UEA-1 | SARLAN LTD (BM) | 2010-03-03 | — | — | EP | disclosed |
| US-7166296-B2 | Pharmaceutical formulations and ligands for use therein; mimetics for UEA-1 | SARLAN, LTD. (BM) | 2007-01-23 | — | — | US | disclosed |
| US-20060276628-A1 | Pharmaceutical Formulations and Ligands for Use Therein; Mimetics for UEA-1 | HOUGHTEN RICHARD | 2006-12-07 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276628-A1 | Pharmaceutical Formulations and Ligands for Use Therein; Mimetics for UEA-1 | UTS2R, PLAUR, HNRNPUL1 | HSD17B2 4809/4885CA12 4043/4885CA1 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.