Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350802 | 0.97 | TSHR (0.73) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL1615353 | 0.97 | TSHR (0.73) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL27743352 | 0.95 | TSHR (0.71) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Acrylic Acid SCHEMBL10484678 | 0.94 | TSHR (0.60) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Methacrylic Acid SCHEMBL12544881 | 0.92 | TSHR (0.67) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Trimethylammonium SCHEMBL6000256 | 0.91 | TSHR (0.65) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Acrylic Acid SCHEMBL1033201 | 0.88 | TSHR (0.88) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Acrylic Acid SCHEMBL28508000 | 0.88 | TSHR (0.88) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Acrylonitrile SCHEMBL2522763 | 0.88 | TSHR (0.61) | TSHRHPGDHCAR2ALDH1A1CYP3A4 | |
| Methacrylic Acid SCHEMBL11308304 | 0.87 | TSHR (0.73) | TSHRHPGDHCAR2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100166695-A1 | Multivalent Heterobifunctional Polymers And Methods Of Their Use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-07-01 | — | — | US | disclosed |
| WO-2007016556-A1 | MULTIFUNCTIONAL POLYMERS FOR PROMOTION OF OPSONIZATION OF TARGET CELLS AND ORGANISMS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-02-08 | — | — | WO | disclosed |
| EP-1125590-B1 | Bioadhesive composition | ROHM & HAAS (US) | 2005-11-02 | — | — | EP | disclosed |
| US-6887960-B2 | Bioadhesive composition | ROHM AND HAAS COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| US-20020007028-A1 | Bioadhesive composition | ROHM AND HAAS COMPANY | 2002-01-17 | — | — | US | disclosed |
| EP-1125590-A2 | Bioadhesive composition | ROHM AND HAAS COMPANY (US) | 2001-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166695-A1 | Multivalent Heterobifunctional Polymers And Methods Of Their Use | PAICS, ILK, PARG | TSHR 2943/4885HPGD 3537/4885HCAR2 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.