Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749356 | 0.82 | CNR1 (0.42) | — | |
| SCHEMBL422451 | 0.76 | CNR1 (0.38) | SCN9A | |
| SCHEMBL30975219 | 0.74 | KMT2A (0.58) | — | |
| SCHEMBL18279086 | 0.74 | KMT2A (0.58) | — | |
| SCHEMBL4772592 | 0.72 | IL1B (0.36) | SCN9A | |
| SCHEMBL752887 | 0.72 | CHRM2 (0.44) | — | |
| SCHEMBL29085188 | 0.72 | KDM4E (0.50) | CNR2SCN9ACFTR | |
| SCHEMBL30064984 | 0.72 | KDM4E (0.50) | CNR2SCN9ACFTR | |
| SCHEMBL27720298 | 0.72 | HIF1A (0.59) | — | |
| SCHEMBL16277582 | 0.71 | P4HTM (0.45) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |