Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31119169 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL651822 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL10394966 | 0.83 | KDM4E (0.70) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL24004168 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL1176635 | 0.80 | MEN1 (0.69) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL4516073 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL10042020 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL5451716 | 0.78 | MAPT (0.68) | ALDH1A1KDM4EMAPTL3MBTL1HPGD | |
| Anthracene SCHEMBL29076817 | 0.78 | MEN1 (0.67) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL19277763 | 0.78 | GAA (0.60) | ALDH1A1KDM4EMAPTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796387-A | The preparation method of thio trifluoroacetyl amine compounds | 温州大学 | 2019-05-24 | — | — | CN | disclosed |