SCHEMBL28294723

SCHEMBL28294723

C[N+](C)(C)CCOC(=O)CC(=O)O.[NaH].[NaH]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.61
ADRA1A P35348 1/20 0.61
MAPT P10636 1/20 0.59
BLM P54132 1/20 0.59
CYP2C19 P33261 2/20 0.57
CHRM1 P11229 8/20 0.56
CHRM3 P20309 8/20 0.56
CHRM2 P08172 7/20 0.56
CHRM4 P08173 7/20 0.56
CHRM5 P08912 6/20 0.56
CHRNB2 P17787 4/20 0.56
CHRNA4 P43681 4/20 0.56
CHRNA7 P36544 3/20 0.56
HTR1A P08908 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
PGR P06401 1/20 0.56
TBXA2R P21731 1/20 0.56
CHRNB4 P30926 1/20 0.56
CHRNA3 P32297 1/20 0.56
CHRNA10 Q9GZZ6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780253 0.98 ADRA2A (0.64) ADRA2AADRA1AMAPTBLMCYP2C19
Hydrochloric Acid SCHEMBL28127021 0.96 MAPT (0.65) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL16353073 0.86 ADRA2A (0.73) ADRA2AADRA1AMAPTBLMCYP2C19
Hydrochloric Acid SCHEMBL28115453 0.83 MAPT (0.55) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL16684872 0.81 ADRA2A (0.59) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL14045415 0.80 CHRM1 (0.64) ADRA2AADRA1AMAPTBLMCYP2C19
Propionic Acid SCHEMBL23044698 0.78 ADRA2A (0.61) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL3037579 0.78 ADRA2A (0.83) ADRA2AADRA1AMAPTBLMCYP2C19
SCHEMBL13346043 0.78 GAA (0.65) ADRA2AADRA1AMAPTBLMCYP2C19
Propionic Acid SCHEMBL19617436 0.77 ADRA2A (0.59) ADRA2AADRA1AMAPTBLMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109789216-B Topical skin treatment formulations based on ionic species 加利福尼亚大学董事会 2023-05-23 CN disclosed
CN-109789216-A Skin treating topical formulations based on ionic species 加利福尼亚大学董事会 2019-05-21 CN disclosed